Why Am I Always Tired?
200+ Causes of Fatigue Explained
Feeling tired all the time? You're not alone. Fatigue is one of the most common health complaints, with dozens of potential causes ranging from simple lifestyle factors to serious medical conditions. This comprehensive guide covers all the reasons you might be feeling exhausted.
Top 10 Most Common Causes of Fatigue
Jump to Section
Sleep-Related Causes
The most common reasons for daily fatigue relate to sleep quantity and quality.
Not enough sleep
Adults need 7-9 hours; consistently getting less leads to sleep debt and chronic fatigue.
Poor sleep quality
Light, fragmented sleep doesn't allow proper restoration even if hours seem adequate.
Insomnia
Learn moreDifficulty falling asleep, staying asleep, or both significantly impacts energy levels.
Waking up unrefreshed
Non-restorative sleep where you wake tired despite sleeping enough hours.
Sleep apnea
Learn moreBreathing pauses during sleep cause oxygen drops and frequent micro-awakenings.
Restless legs syndrome
Learn moreUncomfortable leg sensations and urge to move disrupt falling and staying asleep.
Irregular sleep schedule
Shift work, social jet lag, and inconsistent bedtimes confuse your body clock.
Oversleeping
Paradoxically, sleeping too much (9+ hours) can cause grogginess and fatigue.
Nighttime awakenings
Waking multiple times (bathroom, noise, anxiety) fragments restorative sleep.
Circadian rhythm disruption
When your internal clock is misaligned with your schedule, energy suffers.
Lifestyle & Daily Habits
Your daily choices have a huge impact on energy levels.
Chronic stress
Learn moreProlonged stress keeps cortisol elevated, eventually depleting energy reserves.
Burnout
Learn morePhysical, emotional, and mental exhaustion from prolonged work or life demands.
Dehydration
Learn moreEven mild dehydration reduces blood volume and makes your heart work harder.
Poor diet
Lack of nutrients from processed foods fails to fuel your body properly.
Excessive caffeine
While it boosts alertness short-term, it disrupts sleep and causes crashes.
Alcohol consumption
Alcohol disrupts sleep quality and depletes B vitamins needed for energy.
Smoking/nicotine
Reduces oxygen delivery to tissues and disrupts sleep architecture.
Lack of exercise
Sedentary lifestyle leads to poor circulation and reduced energy production.
Over-exercising
Training too hard without recovery depletes energy stores and causes fatigue.
Sedentary lifestyle
Sitting all day reduces blood flow and makes you feel more tired.
Screen time before bed
Blue light suppresses melatonin and delays sleep onset.
Irregular meals
Skipping breakfast or eating at random times disrupts blood sugar stability.
High-sugar diet
Sugar spikes cause energy crashes and inflammation that drain vitality.
Boredom or monotony
Lack of mental stimulation can manifest as physical tiredness.
Afternoon circadian dip
Natural energy low between 1-3 PM is normal but can feel extreme if sleep-deprived.
Nutrient Deficiencies
Your body needs specific nutrients to produce energy. Deficiencies are very common.
Iron deficiency / anemia
Learn moreWithout enough iron, your blood can't carry sufficient oxygen to tissues.
Vitamin D deficiency
Learn moreLow vitamin D (common in winter/indoor lifestyles) causes fatigue and muscle weakness.
Vitamin B12 deficiency
Essential for red blood cells and nerve function; low levels cause profound fatigue.
Folate deficiency
Works with B12 for cell production; deficiency causes anemia and tiredness.
Magnesium deficiency
Involved in 300+ reactions including energy production; deficiency is widespread.
Vitamin B6 deficiency
Needed for neurotransmitter production and energy metabolism.
Low potassium
Electrolyte imbalance affects muscle function and energy.
Omega-3 deficiency
Essential fats support brain function and reduce inflammation-related fatigue.
Low protein intake
Protein provides building blocks for energy-producing enzymes and tissues.
Overall malnutrition
Restrictive diets or poor food access can cause multiple deficiencies.
Hormonal & Endocrine Issues
Hormone imbalances significantly impact energy levels and metabolism.
Hypothyroidism
Learn moreUnderactive thyroid slows metabolism, causing fatigue, weight gain, and cold intolerance.
Hyperthyroidism
Learn moreOveractive thyroid can cause exhaustion from revved-up metabolism.
Adrenal fatigue / HPA axis dysfunction
Chronic stress can dysregulate the stress response system.
Low testosterone (men)
Declining testosterone causes fatigue, low motivation, and reduced muscle mass.
Menopause / perimenopause
Learn moreHormonal fluctuations cause sleep disruption and fatigue in women.
PCOS-related fatigue
Learn morePolycystic ovary syndrome affects insulin and energy regulation.
Cortisol imbalance
Too high or too low cortisol disrupts energy patterns throughout the day.
Diabetes
Learn moreBlood sugar fluctuations and insulin resistance cause significant fatigue.
Prediabetes
Early blood sugar dysregulation often presents as unexplained tiredness.
Insulin resistance
Cells can't efficiently use glucose for energy, causing fatigue after meals.
Mental Health & Brain-Related
Mental health conditions are major causes of fatigue, often overlooked.
Depression
Learn moreOne of the most common causes of chronic fatigue, often with low motivation.
Anxiety disorders
Learn moreConstant worry and tension exhaust mental and physical resources.
Chronic stress response
Prolonged activation of fight-or-flight depletes energy reserves.
Brain fog
Learn moreCognitive fatigue from stress, illness, or inflammation.
ADHD-related exhaustion
Learn moreThe mental effort to focus and compensate for ADHD is exhausting.
Grief or emotional burnout
Processing loss and intense emotions requires tremendous energy.
Seasonal affective disorder (SAD)
Winter darkness triggers depression and fatigue in susceptible people.
Panic attack aftermath
The adrenaline surge and crash from panic attacks causes exhaustion.
Chronic Conditions & Diseases
Many chronic health conditions have fatigue as a primary symptom.
Chronic fatigue syndrome (ME/CFS)
Learn moreSevere, unexplained fatigue that worsens with exertion and doesn't improve with rest.
Fibromyalgia
Learn moreChronic pain condition that causes profound fatigue and sleep problems.
Autoimmune diseases
Learn moreConditions like lupus, RA, and MS cause fatigue from chronic inflammation.
Heart disease
Poor circulation and reduced cardiac output cause fatigue and breathlessness.
Chronic kidney disease
Toxin buildup and anemia from kidney dysfunction cause severe fatigue.
Liver issues
Liver disease affects metabolism and energy production.
Cancer-related fatigue
Both cancer and its treatments cause significant fatigue.
Multiple sclerosis
MS fatigue is one of the most debilitating symptoms of this condition.
Parkinson's disease
Early Parkinson's often presents with unexplained fatigue.
POTS
Postural orthostatic tachycardia syndrome causes fatigue with position changes.
Lyme disease
Tick-borne illness that can cause persistent fatigue.
Medications & Substances
Many medications list fatigue as a side effect.
Antidepressants
Some antidepressants, especially sedating types, cause daytime fatigue.
Blood pressure medications
Beta-blockers and some others commonly cause tiredness.
Statins
Cholesterol medications can cause muscle fatigue in some people.
Antihistamines
Allergy medications, especially older types, cause drowsiness.
Opioid pain medications
Strong pain relievers cause sedation and fatigue.
Chemotherapy
Cancer treatment commonly causes severe fatigue.
Steroid withdrawal
Stopping corticosteroids can cause fatigue until adrenals recover.
Caffeine withdrawal
Stopping caffeine causes temporary but significant fatigue.
Alcohol withdrawal
Cutting back on alcohol causes fatigue during adjustment.
Sleep aid rebound
Stopping sleep medications can temporarily worsen fatigue.
Other Medical & Physical Factors
Various physical conditions can manifest as fatigue.
Anemia (all types)
Learn moreAny cause of low red blood cells reduces oxygen delivery and energy.
Heart failure
Reduced pumping ability means less oxygen reaches tissues.
COPD / lung issues
Breathing problems reduce oxygen levels and cause exhaustion.
Asthma
Uncontrolled asthma and disturbed sleep from symptoms cause fatigue.
Allergies / sinus problems
Chronic allergies cause inflammation and poor sleep quality.
Chronic pain
Pain is exhausting and disrupts restorative sleep.
Obesity
Excess weight strains the body and is linked to sleep apnea.
Underweight / eating disorders
Insufficient calories means insufficient energy.
Gut issues (IBS, leaky gut)
Learn moreDigestive problems affect nutrient absorption and cause inflammation.
Chronic inflammation
Elevated inflammatory markers (CRP) cause fatigue-inducing cytokines.
Electrolyte imbalance
Low sodium, potassium, or magnesium impairs cellular function.
Age, Life Stage & Environmental
Life circumstances and environment significantly affect energy.
Aging
Metabolism slows, sleep quality decreases, and muscle mass declines with age.
Pregnancy fatigue
Especially in first and third trimesters, pregnancy is exhausting.
Postpartum recovery
New parents face sleep deprivation and physical recovery demands.
Perimenopause
Hormone fluctuations cause sleep disruption and fatigue in women 40s-50s.
Andropause
Gradual testosterone decline in men causes fatigue and low motivation.
Extreme heat/humidity
Hot weather makes your body work harder to cool down.
Pollution exposure
Air pollution increases inflammation and respiratory effort.
Poor indoor air quality
Stuffy, poorly ventilated spaces reduce oxygen and increase CO2.
Noise pollution
Environmental noise disrupts sleep quality even if you don't fully wake.
Shift work disorder
Working against your circadian rhythm causes chronic fatigue.
Psychological & Social Factors
Mental and social factors play a huge role in energy levels.
Overthinking at night
Racing thoughts prevent falling asleep and reduce sleep quality.
Worry about tomorrow
Anticipatory anxiety disrupts rest and recovery.
Perfectionism burnout
Never feeling "good enough" is mentally exhausting.
Caregiver fatigue
Caring for others while neglecting self-care depletes energy.
Student exam stress
Academic pressure combined with poor sleep habits causes exhaustion.
Job loss anxiety
Uncertainty and stress about employment drains energy.
Financial stress
Money worries are a major source of chronic stress and fatigue.
Relationship problems
Emotional turmoil and conflict are exhausting.
Social media overload
Constant comparison and stimulation causes mental fatigue.
Gaming late nights
Video games disrupt sleep schedules and circadian rhythms.
Late-night scrolling
Phone use before bed delays sleep onset and reduces quality.
Dietary & Digestive Factors
What you eat (and how you digest it) directly affects energy.
Fasting gone wrong
Improper fasting can cause blood sugar drops and fatigue.
Keto flu
Transitioning to ketogenic diet often causes temporary fatigue.
Low-carb diet crash
Too few carbs without adaptation causes energy depletion.
Vegan diet deficiencies
Without planning, vegan diets can lack B12, iron, and protein.
Gluten sensitivity
Learn moreNon-celiac gluten sensitivity can cause fatigue in some people.
Dairy intolerance
Lactose or casein intolerance can cause inflammation and fatigue.
Food sensitivities
Reactions to certain foods trigger inflammation and tiredness.
Histamine intolerance
Inability to break down histamine causes various symptoms including fatigue.
SIBO
Small intestinal bacterial overgrowth affects nutrient absorption.
Candida overgrowth
Yeast overgrowth in the gut is associated with fatigue symptoms.
Infections & Toxins
Hidden infections and environmental toxins can cause unexplained fatigue.
Chronic sinus infections
Ongoing sinus issues cause inflammation and poor sleep.
Chronic UTIs
Recurrent urinary infections drain energy and disrupt sleep.
Hidden dental infections
Tooth abscesses can cause systemic inflammation.
Parasitic infections
Intestinal parasites can cause fatigue and nutrient malabsorption.
Mold illness
Exposure to mold in water-damaged buildings causes fatigue in sensitive people.
Sick building syndrome
Poor air quality in buildings causes fatigue and other symptoms.
Heavy metal exposure
Lead, mercury, and other metals can cause chronic fatigue.
Carbon monoxide exposure
Low-level CO exposure causes headaches and fatigue.
Physical Strain & Injury
Physical problems and recovery demands energy.
Post-surgical recovery
The body needs tremendous energy to heal after surgery.
Blood loss
Learn moreHeavy periods, surgery, or injury cause anemia and fatigue.
Chronic pain conditions
Living with pain is exhausting and disrupts sleep.
Poor posture
Muscle strain from poor posture causes physical fatigue.
Eye strain from screens
Digital eye strain causes headaches and mental fatigue.
TMJ disorder
Jaw problems cause headaches and disrupt sleep.
Teeth grinding (bruxism)
Nighttime grinding prevents restful sleep.
Concussion effects
Post-concussion syndrome causes prolonged fatigue.
Whiplash
Neck injuries cause ongoing pain and fatigue.
When to See a Doctor About Fatigue
- •Fatigue lasting more than 2-3 weeks without improvement
- •Unexplained weight loss or gain
- •Severe fatigue that prevents daily activities
- •Fatigue with fever, night sweats, or swollen lymph nodes
- •Shortness of breath or chest pain with fatigue
- •Fatigue after starting a new medication
- •Symptoms of depression or thoughts of self-harm
- •Fatigue that worsens with minimal activity
Common Tests Your Doctor May Order
Quick Tips to Boost Your Energy
Related Condition Pages
Disclaimer: This information is for educational purposes only and does not replace professional medical advice. Fatigue can be a symptom of serious medical conditions. If you experience persistent, severe, or worsening fatigue, please consult a healthcare provider for proper evaluation and diagnosis.