Systemic Lupus Erythematosus (Lupus)
A chronic autoimmune disease where the immune system attacks healthy tissue.
This condition typically requires medical attention
If you suspect you have systemic lupus erythematosus (lupus), please consult a healthcare provider for proper evaluation and treatment.
Overview
Systemic Lupus Erythematosus (SLE), commonly called lupus, is a chronic autoimmune disease where the immune system attacks healthy tissues throughout the body. It can affect the skin, joints, kidneys, brain, heart, lungs, and blood cells. Symptoms vary widely and often mimic other conditions, making diagnosis challenging. Lupus tends to flare and remit. While there's no cure, treatment can help control symptoms and prevent organ damage.
Common Age
Usually 15-45; most common in women of childbearing age
Prevalence
Affects about 1.5 million Americans; 9x more common in women
Duration
Lifelong chronic condition with flares and remissions
Common Symptoms
- Butterfly-shaped rash across cheeks and nose
- Joint pain, stiffness, and swelling
- Extreme fatigue
- Fever
- Photosensitivity (sun sensitivity)
- Hair loss
- Mouth or nose ulcers
- Raynaud's phenomenon (fingers turn white/blue in cold)
- Chest pain when breathing deeply
- Headaches and confusion
- Kidney problems
Possible Causes
- Immune system dysfunction
- Genetic predisposition
- Hormonal factors (more common in women)
- Environmental triggers (sunlight, infections)
- Certain medications can trigger drug-induced lupus
- Stress may trigger flares
Note: These are potential causes. A healthcare provider can help determine the specific cause in your case.
Quick Self-Care Tips
- 1Protect yourself from sun (SPF 50+, protective clothing)
- 2Get adequate rest
- 3Exercise gently and regularly
- 4Don't smoke
- 5Eat a healthy diet
- 6Manage stress
- 7Take medications as prescribed
- 8Keep all medical appointments
Disclaimer: These are general wellness suggestions, not medical treatment recommendations. They may help manage symptoms but should not replace professional medical care.
Detailed Treatment & Solutions
1NSAIDs
For mild joint pain and fever. Ibuprofen, naproxen. Watch for stomach and kidney side effects.
2ANTIMALARIALS
Hydroxychloroquine (Plaquenil) is cornerstone of lupus treatment. Reduces flares, protects organs. Requires eye exams.
3CORTICOSTEROIDS
Prednisone for moderate-severe flares. Effective but many side effects with long-term use. Goal is lowest effective dose.
4IMMUNOSUPPRESSANTS
Azathioprine, mycophenolate, methotrexate for organ involvement. Require monitoring.
5BIOLOGICS
Belimumab (Benlysta), rituximab for refractory cases. Target specific immune pathways.
6SUN PROTECTION
Critical to prevent flares. SPF 50+ daily. Protective clothing, hats. Avoid peak sun hours.
7MONITORING
Regular blood tests, urine tests. Monitor kidney function, blood counts. Cardiovascular screening.
Important: Always consult a healthcare professional before starting any treatment regimen. The solutions above are for educational purposes and may not be suitable for everyone.
Risk Factors
- Female gender
- African, Asian, Hispanic ancestry
- Family history
- Certain medications
Prevention
- Cannot be prevented; early diagnosis and treatment prevent complications
When to See a Doctor
Consult a healthcare provider if you experience any of the following:
- Unexplained rash, especially on face
- Persistent fatigue and joint pain
- Fever without obvious cause
- Signs of kidney problems (swelling, foamy urine)
- Chest pain or shortness of breath
- Any new or worsening symptoms
Talk to a Healthcare Provider
If your symptoms are persistent, severe, or concerning, please consult with a qualified healthcare professional for proper evaluation and personalized advice.
Frequently Asked Questions
QIs lupus fatal?
With modern treatment, most people with lupus live normal or near-normal lifespans. The key is early diagnosis, proper treatment, and regular monitoring. Complications like kidney disease or cardiovascular problems need careful management. Work closely with your healthcare team.
QCan lupus go into remission?
Yes, lupus often has periods of remission where symptoms are minimal or absent. Some people achieve long-term remission with proper treatment. However, flares can still occur, so ongoing monitoring and preventive measures (like sun protection) remain important.
Related Conditions
Fibromyalgia
A disorder causing widespread musculoskeletal pain, fatigue, and tender points.
Fibromyalgia
A chronic condition causing widespread pain, fatigue, sleep problems, and cognitive difficulties.
Rheumatoid Arthritis
An autoimmune disease causing chronic inflammation of the joints.
Fibromyalgia
Chronic widespread pain and fatigue with no identifiable cause.
Was this information helpful?
Your feedback is anonymous and helps us improve our content.
Medical Disclaimer
The information on this page is for educational purposes only and is not intended as medical advice. It should not be used for self-diagnosis or self-treatment. Always seek the guidance of a qualified healthcare professional with any questions you have regarding a medical condition. If you are experiencing a medical emergency, call your local emergency services immediately.
Information last reviewed: January 2026
This page provides educational information only. It is not medical advice.