Lupus Fatigue
Severe fatigue affecting most people with systemic lupus erythematosus.
What is Lupus Fatigue?
Common Age
Lupus typically diagnosed 15-45
Prevalence
Affects 80-90% of lupus patients
Duration
Chronic; fluctuates
Common Symptoms
- Severe persistent fatigue
- Unrefreshing sleep
- Cognitive dysfunction (lupus fog)
- Muscle weakness
- Reduced activity tolerance
- Fatigue worsening with flares
Possible Causes
- Chronic inflammation
- Disease activity
- Depression
- Anemia
- Thyroid dysfunction
- Medications
- Sleep disorders
- Fibromyalgia (common comorbidity)
Note: These are potential causes. A healthcare provider can help determine the specific cause in your case.
Quick Self-Care Tips
- 1Work with rheumatologist on disease control
- 2Screen for depression
- 3Check for anemia and thyroid
- 4Prioritize sleep
- 5Pace activities
- 6Avoid sun (triggers flares)
Disclaimer: These are general wellness suggestions, not medical treatment recommendations. They may help manage symptoms but should not replace professional medical care.
Detailed Treatment & Solutions
1DISEASE CONTROL
Better disease management generally improves fatigue.
2TREAT COMORBIDITIES
Depression, fibromyalgia, sleep disorders, anemia.
3LIFESTYLE
Pacing, gentle exercise, stress management, sun protection.
4VITAMIN D
Deficiency common in lupus (sun avoidance); supplement if low.
Important: Always consult a healthcare professional before starting any treatment regimen. The solutions above are for educational purposes and may not be suitable for everyone.
Risk Factors
- Active disease
- Fibromyalgia
- Depression
- Sleep problems
Prevention
- Good disease management
- Avoiding triggers
When to See a Doctor
Consult a healthcare provider if you experience any of the following:
- Fatigue significantly affecting life
- Signs of disease flare
- Depression symptoms
- New symptoms
Talk to a Healthcare Provider
If your symptoms are persistent, severe, or concerning, please consult with a qualified healthcare professional for proper evaluation and personalized advice.
Frequently Asked Questions
QWhy do I still have fatigue when my lupus is controlled?
Fatigue in lupus is multifactorial. Even with disease control, depression, sleep problems, deconditioning, and other factors contribute. Address all aspects.
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Medical Disclaimer
The information on this page is for educational purposes only and is not intended as medical advice. It should not be used for self-diagnosis or self-treatment. Always seek the guidance of a qualified healthcare professional with any questions you have regarding a medical condition. If you are experiencing a medical emergency, call your local emergency services immediately.
Information last reviewed: January 2026
This page provides educational information only. It is not medical advice.